Earn point on your loyalty program!arrow arc left

Cheap flights from Raleigh Durham (RDU) to Santiago (SCL)

Know your dates, get live prices in seconds
airplane logo

pin logo

calendar
Departure
calendar backward
Return
airplane logo
1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
Save up to 31%
Book Flight + Hotel at the same time

How to find the cheapest flight from Raleigh Durham (RDU) to Santiago (SCL)

How to find the cheapest flight from Raleigh Durham (RDU) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.

Cheap flights from Raleigh Durham to Santiago in September , October 2026

30 Sep - 24 Oct $ 757.00
RDU
Raleigh Durham
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
2 STOPS
RDU
Raleigh Durham
Pick dates
30 Sep - 04 Oct $ 1,539.00
RDU
Raleigh Durham
Copa Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
Copa Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates
29 Sep - 04 Oct $ 1,539.00
RDU
Raleigh Durham
Copa Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Copa Airlines
1 STOPS
RDU
Raleigh Durham
Pick dates

Last minute flights from Raleigh Durham to Santiago

28 Sep - 01 Oct $ 990.00
RDU
Raleigh Durham
BREEZE
2 STOPS
SCL
Santiago
SCL
Santiago
BREEZE
2 STOPS
RDU
Raleigh Durham
Pick dates
28 Sep - 30 Sep $ 3,024.00
RDU
Raleigh Durham
Air Canada
2 STOPS
SCL
Santiago
SCL
Santiago
Air Canada
2 STOPS
RDU
Raleigh Durham
Pick dates
28 Sep - 30 Sep $ 3,280.00
RDU
Raleigh Durham
Air Canada
1 STOPS
SCL
Santiago
SCL
Santiago
Air Canada
2 STOPS
RDU
Raleigh Durham
Pick dates

One-way flights to Santiago from Raleigh Durham

10:07 AM - 11:10 PM
LATAM Airlines
2 Stops
19h 53m
RDU - SCL
$ 400
Kiwi
Pick dates
1:42 PM - 12:05 AM
LATAM Airlines
2 Stops
14h 58m
RDU - SCL
$ 685
Kiwi
Pick dates
6:31 PM - 10:05 PM
LATAM Airlines
1 Stops
12h 44m
RDU - SCL
$ 690
Kiwi
Pick dates

How to find the cheapest flight from Raleigh Durham (RDU) to Santiago (SCL)

Related info for your journey
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from Raleigh Durham (RDU) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.