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Cheap flights from San Francisco (SFO) to Santiago (SCL)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from San Francisco (SFO) to Santiago (SCL)

How to find the cheapest flight from San Francisco (SFO) to Santiago (SCL)
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How to find the cheapest flight from San Francisco (SFO) to Santiago (SCL)
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How to find the cheapest flight from San Francisco (SFO) to Santiago (SCL)
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Cheap flights from San Francisco to Santiago in April , May 2026

11 Apr - 10 May $ 729.00
SFO
San Francisco
Avianca
2 STOPS
SCL
Santiago
SCL
Santiago
Avianca
2 STOPS
SFO
San Francisco
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14 Apr - 02 May $ 799.00
SFO
San Francisco
Avianca
1 STOPS
SCL
Santiago
SCL
Santiago
Avianca
2 STOPS
SFO
San Francisco
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06 Apr - 07 May $ 1,087.00
SFO
San Francisco
LATAM Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
LATAM Airlines
1 STOPS
SFO
San Francisco
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Last minute flights from San Francisco to Santiago

11 Apr - 30 Apr $ 791.00
SFO
San Francisco
Avianca
2 STOPS
SCL
Santiago
SCL
Santiago
Avianca
2 STOPS
SFO
San Francisco
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10 Apr - 30 Apr $ 791.00
SFO
San Francisco
Avianca
2 STOPS
SCL
Santiago
SCL
Santiago
Avianca
2 STOPS
SFO
San Francisco
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14 Apr - 30 Apr $ 1,002.00
SFO
San Francisco
Copa Airlines
1 STOPS
SCL
Santiago
SCL
Santiago
Copa Airlines
1 STOPS
SFO
San Francisco
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One-way flights to Santiago from San Francisco

11:55 PM - 4:20 PM
Avianca
2 Stops
20h 25m
SFO - SCL
$ 451
Kiwi
Pick dates
1:23 AM - 11:48 AM
Copa Airlines
1 Stops
15h
SFO - SCL
$ 479
Kiwi
Pick dates
1:23 AM - 11:48 AM
Copa Airlines
1 Stops
15h
SFO - SCL
$ 479
Kiwi
Pick dates

How to find the cheapest flight from San Francisco (SFO) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from San Francisco (SFO) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from San Francisco (SFO) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.