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Cheap flights from St Louis (STL) to Santiago (SCL)

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1 Adults (11+)
0 Children (2~11)
0 Infants (0~2)
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How to find the cheapest flight from St Louis (STL) to Santiago (SCL)

How to find the cheapest flight from St Louis (STL) to Santiago (SCL)
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How to find the cheapest flight from St Louis (STL) to Santiago (SCL)
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How to find the cheapest flight from St Louis (STL) to Santiago (SCL)
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Cheap flights from St Louis to Santiago in March , April 2026

29 Mar - 18 Apr $ 699.00
STL
St Louis
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
3 STOPS
STL
St Louis
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29 Mar - 25 Apr $ 699.00
STL
St Louis
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
3 STOPS
STL
St Louis
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29 Mar - 10 Apr $ 747.00
STL
St Louis
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
2 STOPS
STL
St Louis
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Last minute flights from St Louis to Santiago

29 Mar - 01 Apr $ 860.00
STL
St Louis
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
3 STOPS
STL
St Louis
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30 Mar - 01 Apr $ 860.00
STL
St Louis
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
3 STOPS
STL
St Louis
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23 Mar - 01 Apr $ 860.00
STL
St Louis
Frontier Airlines
2 STOPS
SCL
Santiago
SCL
Santiago
Frontier Airlines
3 STOPS
STL
St Louis
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One-way flights to Santiago from St Louis

7:52 AM - 7:25 PM
Copa Airlines
2 Stops
18h 6m
STL - SCL
$ 387
Kiwi
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7:47 AM - 7:25 PM
Copa Airlines
2 Stops
18h 11m
STL - SCL
$ 387
Kiwi
Pick dates
7:47 AM - 7:25 PM
Copa Airlines
2 Stops
18h 11m
STL - SCL
$ 387
Kiwi
Pick dates

How to find the cheapest flight from St Louis (STL) to Santiago (SCL)

Related info for your journey
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How to find the cheapest flight from St Louis (STL) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.
How to find the cheapest flight from St Louis (STL) to Santiago (SCL)
Some placeholder content for the first accordion panel. This panel is shown by default, thanks to the .show class.